The creators of "South Park," Andrew Sullivan and comedian Louis C.K. defied conventions by going solo with their own media companies. But what does it take to ensure indie media success? Amanda Palmer, singer for The Dresden Dolls, spoke to HuffPost Live host Mike Sacks on Tuesday about going from end to end of the indie spectrum.

Palmer went from busking on the sidewalk for years, to raising over a million dollars on Kickstarter for her solo album, which became a top ten hit last year. Looking forward, she argues that there's no single answer for what will work for independent artist and journalists.

"I think there's going to be as many different systems as there are outlets and artists, and I think trying to make a blanket rule about what will work for journalists, or what will work for musicians, or what will work for authors, is kind of the wrong conversation," Palmer told HuffPost Live.

Instead, Palmer focuses on using technology to present a unique approach to fans, saying "the cool thing about the Internet now is that you can totally personalize and customize your little system."

"Donnie Darko" producer Hunt Lowry also joined the conversation, saying that "there's always a few lucky breaks" in the world of independent film production, adding that producers need to be on as many platforms as possible, including the Internet, television, cable, and home video.

"You may be small and independent, but you still want it to be seen by as many people as possible," Lowry said.